Abstract
This paper is the result of multi-annual research of the ichthyofauna of the main aquatic ecosystems in the Republic of Moldova. It was highlighted the particularities of ichthyofaunistics succession, the negative ecological factors and it was elaborated the recommendations for the protection and improvement of the fishery fund. Thus, in the conditions of fragmentation rivers, excessive fishing, pollution of the aquatic ecosystems and rapid climate changes it is noted "artificial enriching" the number of species, which is based on anthropocorous translocation and self-expansion of new opportunistic species

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